× HOME PHARMACOKINETICS PHARMACODYNAMICS DISSOLUTION IVIVC TOXICOKINETICS INTERSPECIES SCALING SIMULATION dEq VALIDATION VIDEOS
  • PKMP Banner
    PKMP ipad View

PKMP

A Comprehensive Software Solution for

Pharmacokinetics

Biopharmaceutics

Pharmacodynamics


Consultancy Services

Clinical Pharmacology

Nonclinical Pharmacokinetics and Metabolism Studies

Bioanalysis and Management

Data Analysis and Reporting

Team Representation and Strategic Planning

Scientific Publications

Regulatory Support ( IND, NDA and MAA)

Welcome to APL

APL LLC has been incorporated in early 2015 in USA. APL is pharma software solution and consulting services company supporting pharmaceutical research and development. Our software, pharmacokinetic modeling program (PKMP) will support data analysis in the following key areas of drug development: lead identification / optimization, dose response analysis, bioequivalence analysis of products, in vitro-in vivo correlations for formulations, dissolution data analysis, modeling and predictions.

APL LLC has started its operations in Bangalore, India by forming the APL Analyst IT Solutions Pvt Ltd company in May 2018, with the vision of software services and product development. Currently APL Analyst IT Solutions has a workforce of 20-25 programmers and testers working on a permanent and contractual basis who are diligently engaged with multiple clients for software development, testing, and maintenance of a variety of projects. We have 20+ years of IT solutions experience, product development, customized software developments, web and cloud solutions, security solutions for multiple industries including the banking, automobiles, retails, telecom, and manufacturing. We specialize in data analytics and artificial intelligence.

APL has following products and services:

  • Pharmacokinetic modeling program (PKMP)
    • Pharmacokinetic, pharmacodynamic, dissolution, and in vitro-in vivo correlation data analysis
  • Services for
    • PK data analysis and reporting
    • Clinical pharmacology study designs and execution
    • Animal pharmacokinetic and metabolism study design and execution
    • Management of bio-analysis
    • Preparation of PK sample labeling, supplies and shipment
    • Regulatory submissions (INDs, NDAs, MAA)
    • Project team representation and strategic planning
    • In/out licensing
    • Scientific publications
welcome

PKMP

THE MOST COMPLETE DATA ANALYSIS TOOL

Our software, pharmacokinetic modeling program (PKMP) will support data analysis for pharmacokinetic, clinical pharmacology, biopharmaceutics, and dissolution needs of new drug and generic product developments. These analyses are critical in drug development for cost and time savings.

PKMP will support data analysis in the following key areas of drug development: lead identification/optimization, dose response analysis, bioequivalence analysis of products, in vitro-in vivo correlations for formulations, dissolution data analysis, modeling and predictions.

Our consultancy services include nonclinical and clinical pharmacokinetics, biopharmaceutics, bioanalysis, and drug metabolism aspects during different phases of drug development as well as for generic drug products development. We get involved from planning through execution and regulatory submission needs of pharmaceutical business.

support

PKMP Features

WE TRULY CARE ABOUT OUR CUSTOMERS

PKMP Software For Pharma R&D

Noncomparmental PK analysis

Compartmental PK Analysis

Dissolution Data Analysis

In vitro – in vivo Correlation

Simulation

Reporting

Validation

Noncompartmental Analysis

Plasma PK Analysis

Urine PK Analysis

Superposition Analysis

Toxicokinetics

Interspecies Scaling

BE 2x2 crossover,

Repeated BE,

Anova,

Dose proportionality

Compartmental Analysis

Pharmacokinetics

Oral (1CBM, 2CBM)

Intravenous (1CBM, 2CBM, 3CBM)

Intravenous infusion (1CBM, 2CBM, 3CBM)

Pharmacodynamics

Emax

Sigmoidal Emax

Inhibitory Emax

Sigmoidal inhibitory Emax

Dissolution

Dissolution Models

Profile Comparisons

Multivariate statistical distance

In vitro-in vivo Correlation

Loo-Riegelman Method

Numeric Deconvolution

Wagner-Nelson Method

Level A correlation

Convolution

Levels A, B, C, and Levy Plots

Simulations

Pharmacokinetic

Pharmacodynamic

IVIVC

Sample size calculation

PKMP Modules

WE TRULY CARE ABOUT OUR CUSTOMERS

Absorption, distribution, metabolism, and elimination

A relationship between the concentration and a response

The process of dissolving a drug substance from the solid state

In vitro –in vivo correlation for modified release dosage forms

Limited sampling data analysis in animal toxicity studies

Evaluating relationships based on mathematical models

A process of checking software system meets specifications

For background and how to perform different analysis

Release Notes

WE TRULY CARE ABOUT OUR CUSTOMERS

Sl No. Name Version Release Date Status
1. PKMP Release Note 1.03.31 02-November-2020 View
2. PKMP Release Note 1.03.30 09-October-2020 View
More Releases...

Request For A Demo & Quote

WE TRULY CARE ABOUT OUR CUSTOMERS

DEMO REQUEST
  • Gain A brief
  • idea about the
  • product by spending
  • a few minutes
  • with us
Click Here
QUOTE REQUEST
  • We are always
  • happy to get
  • involved with
  • your query
  • and the questions
Click Here
PURCHASE
  • Buy only
  • because it
  • excites you for being
  • the new innovative
  • tool for your needs

APL- PKMP Software Quality Statement

WE TRULY CARE ABOUT OUR CUSTOMERS

The APL PKMP software application team brings in several decades of experience in the pharma, banking, telecom, and defense industries. Our primary experience includes development of software-based systems and applications that are subjected to meeting industry and government regulations. The software developer, programmers, and tester have appropriate training and experience to develop the product, PKMP software.

APL philosophy is to produce a high quality product that requires paying attention to all the stages of software development life cycle starting from requirements gathering and analysis, design documentations, implementation, code reviews, verification and validation testing, production deployment, and production support. High quality in the final product is achieved only by ensuring quality is embedded in every stage of the product development.

IT Services

WE TRULY CARE ABOUT OUR CUSTOMERS

  • IT Services
  • Product Development
  • Open Source Customization
  • Staffing Solutions

http://www.aplprojects.in

  • Building flexible and scalable technical teams for the clients based on the technical requirements and budget
  • High quality and efficient resources with exact match for the given requirement
  • Cost effective and Highly Skilled resources
  • Pre Interview
  • Shorter Hiring cycle
  • Flexible Engagement (Contracts / Subcontracts / Contract to Hire / Direct placements)
  • IT Solutions
  • Product Development
  • Custom software Developments
  • Web and Mobile App Development
  • Cloud Solutions
  • Security Solutions
  • Data Analytics
  • Artificial Intelligence

Our Team

WE TRULY CARE ABOUT OUR CUSTOMERS

card image

Ajit Shah (Ph.D.)

Founder and president

Ajit Shah

More than 25 years of experience in pharmaceutical industry (Pfizer, Marion Merrel Dow, MGI Pharma Inc., and Sun Biopharma Inc.). Expertise in drug development and regulatory submissions to FDA and regulatory agencies in Europe and Japan. Expertise in developing anticancer drugs.

card image

Santosh Sonbarse (MS, MBA)

Technical officer

Santosh Sonbarse

More than 25 years of experience in engineering and product development. Expert in software development life cycle projects, and people management. Management experience working for several fortune 500 organizations - frontier comunications, general dynamics, target, and ADC telecom.

card image

Darshan Sonbarse (B. Tech.)

Software officer

Darshan Sonbarse

An IT professional with 20 years of experience in application development, maintenance, and performance engineering. Experience in providing integrated solutions, application performance management and process automation across the wide range of technologies platforms and business domains.

Contact Us

WE TRULY CARE ABOUT OUR CUSTOMERS

Tell us a few things about yourself

Thanks for your request. Demo link and login credentials are sent to your mail please check your inbox.
[SMTP] Error! Internal server error!
Sorry! You need to complete all mandatory (*) fields!
   
captcha


Visit Us

Address: APL ANALYST IT SOLUTIONS PVT. LTD. WS365, 3rd Floor, 27 main Rd, 1st Sector, HSR Layout, Bengaluru, Karnataka, 560102, INDIA Phone: (+91) 80 4149 5681 Email: info@aplanalyst.com


Address: APL 9671 Laforet drive, Eden Prairie, MN 55347, USA Phone:(+1) 952-294-9868 Email: ajit.shah@aplanalyst.com