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 PKMP Release Notes


Modules Impacted

  1.  IVIVC
  2.  Simulation

Bug Fixes:

  1.  IVIVC Level B and Level C graph changes. (#200)
  2.  Addition of download option and decimal and significant number buttons to the IVIVC Level B and Level C analyses. (#201)
  3.  BE simulation calculation. (#202)

Modules Impacted

  1.  NCA-PK
  2.  IVIVC
  3.  Differential Equation (dEq)
  4.  Reports

Bug Fixes:

  1.  In IVIVC Vitro analysis the graph title name is repeated. (#191)
  2.  In IVIVC "level C" graph ploting is incorrect. (#192)
  3.  In IVIVC "level B" analysis the data should be displayed. (#193)
  4.  In NCA-Extravaslular AUC Calculation and KEL Plot should be calculated with any type of dataset. (#194)
  5.  For IV Blous and Infusion need to implement the above code. (#195)
  6.  NCA(Extravascular,Bolus,Infusion) Reporting data should be displayed liked the analysis performed. (#196)
  7.  dEq-User Defined conc calculation is not performed for some analysis. (#197)
  8.  SD error bar graph issue is fixed. (#198)
  9.  Increased the logout time for a session. (#199)

Modules Impacted

  1.  NCA-PK
  2.  Differential Equation (dEq)
  3.  Upload Module
  4.  Reports

New Features/ Enhancements:

  1.  dEq module Back button implementation (#186).
  2.  dEq module, Concentration calculation should be based on volume (#187).
  3.  Dose Proportionality, back end code enhancement (#55).

Bug Fixes:

  1.  dEq infusion module, calculations were not coming properly (#185).
  2.  Dose Proportionality, history tab was not coming in downloaded files (#184).
  3.  SD & SE error bars were not coming for few Descriptive Statistical analysis (#84).
  4.  Reporting Module, auc(0-inf) value is not coming properly in reports for NCA Oral & Bolus module (#188).
  5.  Upload module, error was coming while clicking on upload button without selecting any file instead of message (#189).

Modules Impacted

  1.  NCA-PK
  2.  Differential Equation (dEq)

New Features/ Enhancements:

  1.  dEq Module: User Defined Equation (#44)

Bug Fixes:

  1.  Fixed the issue of HED animal to animal prediction (#178)
  2.  Fixed the issue of History tab in downloaded file of Dose Proportionality. (#184)

Modules Impacted

  1.  NCA-PK
  2.  CA-PK
  3.  PD
  4.  Dissolution
  5.  IVIVC Model
  6.  Simulation
  7.  Reports

Bug Fixes:

  1.  Descriptive graph log scale display. (#171)
  2.  Missing Y-axis graph labels throughout the application. (#164)
  3.  Changing subject-wise Cp vs time graph from linear to log linear and vice versa. (#170)
  4.  PD report module with group selection. (#108)
  5.  NCA module- Point Removal log-linear graph. (#182)

Modules Impacted

  1.  PD
  2.  Dissolution
  3.  IVIVC
  4.  Simulation

New Features/ Enhancements:

  1.  History tab is added in all the file downloads in PD, Dissolution, IVIVC and Simulation modules. (#127)
  2.  Enhancement to stop junk e-mails generated from Contact Us page on the website by the bots. (#168)

Bug Fixes:

  1.  Older version number was showing in history tab of PD module. (#172)
  2.  In Dissolution module, table was repeating while downloading in doc file. (#173)
  3.  In Dissolution module, header name was missing in downloaded tables for "profile comparison" & "MSD Determination”. (#174)
  4. IVIVC Module, table header was repeating in downloaded files. (#175)
  5. Dissolution Module, download button of doc and csv is not working in Weibull Analysis. (#176)

Modules Impacted

  1.  NCA-PK
  2.  CA-PK
  3.  IVIVC
  4.  Differential Equation (dEq)

New Features/ Enhancements:

  1.  History tab is added in all the file downloads in NCA, CA and dEq modules. (#127)

Bug Fixes:

  1.  Toxicokinetics without Dose analysis should provide the option to the users to enter Dose. (#139)
  2.  For IVIVC Numerics module IR-IV Cp data to be at equivalent dose level to the in-vivo Cp data requirement is added. (#72)

Modules Impacted

  1.  NCA-PK

Bug Fixes:

  1.  The graph in NCA-PK should plot greater than zero values and zero should not display on log scale. (#162)
  2.  Interspecies Scaling : Method 1 - Unit issues in Human Prediction. (#161)
  3.  Interspecies Scaling : Method 2 - calculation of Mean and SD when one or two species are selected. (#161)

Modules Impacted

  1.  Login module
  2.  NCA-PK
  3.  CA-PK
  4.  PD
  5.  Dissolution
  6.  IVIVC
  7.  Simulation
  8.  Differential Equation (dEq)
  9.  Repots

New Features/ Enhancements:

  1.  Interspecies clearance (Cl) and volume distribution (Vd) calculations (#153)
  2.  Addition of delete button in Reports module (#152)
  3.  Captcha feature is disabled for internal automation testing only (#151)
  4.  Addition of dEq in the Reports module (#131)
  5.  Code changes to support internal automation testing without Captcha login (#158)
  6.  Addition of release note in website and PKMP application (#159)
  7.  Addition of DF and SF in BE ratio analysis (#154)

Bug Fixes:

  1.  Fixed the issue with column-wise filters not working everywhere (#133)
  2.  Icon for Dissolution UI fixed (#132)
  3.  Superposition all graphs issue fixed (#150)
  4.  DF & SF download issues fixed in Firefox (#65)
  5.  Made the Download feature of Differential module consistent with other modules.(#156)
  6.  Fixed the issue with the download functionality of Dose proportionality and removed default dose selection checkbox (#155)

Modules Impacted

  1.  Login module
  2.  NCA-PK
  3.  CA-PK
  4.  PD
  5.  Dissolution
  6.  IVIVC
  7.  Simulation
  8.  Differential Equation (dEq)
  9.  Validation
  10.  Profile

New Features/ Enhancements:

  1.  Login Captcha: Captcha is required while Login to induce one more level of Security
  2.  IP Validation enhancements: To restrict an user with expired license
  3.  Security Policies - Update password, Reset password, Encryption (AES 256-bit)
  4.  dEq download module enhancements: Analysis results and graphs are downloaded in one report file
  5.  Toxicokinetics- clearence (Cl) and volume distribution (Vd) enhancements in Analysis and Report: Normalized values of Cl and Vd have been calculated and displayed in UI and Reports

Bug Fixes:

  1.  CA-PK predicted table repeating issue
  2.  Dissolution global decimal number setting issue
  3.  Dissolution analysis result download issue
  4.  NCA-PK issues (downloaded analysis result files were blank, changing one column was affecting other columns, repeating table, display issue in point selection page and All Subjects page)
  5.  Decimal and significant figures issues (all modules)